Large-volume HA filler injections can lead to bone resorption in the chin

Hyaluronic acid injections can induce bone resorption in the mentum, found a study published in Plastic and Reconstructive Surgery. 

The authors set out to analyse the impact of hyaluronic acid on bone resorption in the protruding part of the chin, otherwise known as the mentum, and the influencing factors. 

From a group of 80 patients and 80 controls, the authors compared the computed tomographic scans of patients with or without mentum augmentation using hyaluronic acid.

Semimandibular bone resorption index was calculated as the ratio of bone thickness in the incisive fossa to that in the mandibular symphysis. Injection volume, injection interval, the number of injections, product and any complication were also recorded.

Patients injected with greater than or equal to 1ml per time were more susceptible to bone erosion compared with patients injected with less. There was no significant difference between one injection or multiple injection groups and short-injection-interval versus long-injection-interval (≥6 months) groups.

It was concluded that hyaluronic acid injection could induce bone resorption in the mentum; though the aesthetics were not impaired. The severity of the bone loss was positively correlated with the injection volume per time; therefore, large-volume injection of hyaluronic acid should be performed with caution.

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