AMP brings plant-based exosome technology to the UK market

As exosomes become an increasingly popular buzzword in the aesthetic industry, the UK’s first completely plant-derived exosome product - EXO|E Revitalizing Complex - has been made available to the UK market, via Aesthetic Medical Partnership (AMP).

The potential applications of exosomes within aesthetics include skin regenerative functions, anti-inflammatory effects, and synergistic use alongside energy-based devices to enhance healing and lessen downtime.

However, with the continued controversies surrounding human sources of exosomes, it is plant-based alternatives - known as PDENs (Plant Derived Extracellular Nanoparticles) that are garnering particular attention.

EXO|E’s patented biomimetic technology harnesses the power of PDENs, which are extracted from plant stem cells and act like envelopes that carry messages from cell to cell. These envelopes are loaded with thousands of biomimetic factors that are compatible with the skin and help to support and supplement its natural signalling mechanism.

These biomimetic factors include growth factors, peptides, liposomes, amino acids, and proteins directed explicitly to target inflammation, wound healing angiogenesis, and the stimulation of hyaluronic acid, collagen, and elastin production. This shift from inflammation to rejuvenation means less downtime and enhanced results.

One of the notable reported advantages of EXO|E is its ability to penetrate the skin transdermally through lipophilic absorption. This enables the comprehensive treatment of the entire dermal architecture through efficient cell-to-cell signalling. Studies also show that EXO|E can increase collagen production by 165%, elastin by 891%, the secretion of hyaluronic acid by 198%; and provide a 61% daily reduction in inflammation.

Suitable for all skin types and conditions, the complete treatment protocol includes D|TOX, EXO|E, and RE|PAIR, which can be used both in-clinic and at home to prepare skin pre-procedure or enhance treatment outcomes. It can also be used as a stand-alone treatment.

D|TOX hydrates and prepares the skin for upcoming treatments; the EXO|E serum delivers concentrated stem cell factors for targeted results; and the RE|PAIR serum reinforces the work of EXO|E with additional extracellular nanoparticle technology and liposomes.

“I am excited to be the first clinic in the UK and Europe and one of the first globally, outside of the US, to introduce the UK’s first completely plant-derived exosome product,” says the surgeon, cosmetic doctor and medical director of S-Thetics Clinic, Miss Sherina Balaratnam.

“I have spent over eight years understanding ingredient formulations and the science behind how botanically derived topical skincare works,” Miss Balaratnam continues. “I have curated bespoke protocols with these topicals to produce highly regenerative results for my patients. Together with my previous knowledge and understanding of cell signalling from my research time at the University College of London (UCL 2004-5), these learnings have developed my knowledge of regenerative skin science.

“EXO|E delivers the next phase of topicals to fill in the missing links, such as the regeneration of one’s own elastin, hyaluronic acid, and collagen production, up-regulated endogenously,” concludes Miss Balaratnam. “This is only the second skincare system I have introduced to my clinic after eight years, illustrating the depth and breadth of the robust science, clinical validation, and manufacturing processes behind EXO|E.”

To find out more, visit amp-uk.co.uk