Did you know that recent research indicates that UV-induced oxidative stress exacerbates glycation, leading to wrinkles, sagging skin, and a dull complexion?
Glycation is a process where sugars bind to the skin’s structural proteins, like collagen and elastin, forming molecules known as Advanced Glycation End-Products (or A.G.Es). From your 20s, A.G.Es accumulate at about 3.7% per year, reducing skin firmness, elasticity, and radiance while increasing dryness.1,2
For over 15 years, SkinCeuticals has researched glycation, also known as the Maillard reaction, which unfolds in three phases. During the initiation and propagation phases, early glycation products emerge, providing a critical opportunity for intervention before the formation of irreversible A.G.Es in the advanced phase.
Research indicates that UV-induced oxidative stress exacerbates glycation, with sun-exposed skin showing a 10% higher A.G.E-CML score, a primary indicator of glycation damage. This effect is intensified by factors like cigarette smoke, alcohol, and dietary choices. SkinCeuticals’ ex-vivo studies showed that skin under glycation stress, when treated with SkinCeuticals A.G.E. Interrupter Ultra Serum, significantly reduced A.G.E formation in both the dermis and epidermis, lowering the CML biomarker by 43% and 69%, respectively, compared to the control.^
SkinCeuticals A.G.E. Interrupter Ultra Serum
SkinCeuticals, a leader in anti-ageing skincare, introduces A.G.E. Interrupter Ultra Serum. This triple-patented formula visibly lifts and firms by targeting glycation's effects. Ideal for sagging, wrinkles, and dullness, it's suitable for all skin types, even sensitive skin.
Key ingredients:
• 34.6% Flavo-Proxylane™: Combines 30% Proxylane for firmness and wrinkle reduction with 4.6% wild fruit flavonoids (blueberry, pomegranate, and new cassia alata extract) to combat oxidative stress and protect against free radicals
• Rhamnose: This hydrating anti-ageing sugar boosts skin's appearance and enhances elasticity
• Gentiana lutea root extract: A potent antioxidant that supports and protects collagen.
Clinical studies and results:
Clinical studies show Improvements in skin elasticity and firmness across key facial areas, including the forehead (+7.6%), cheeks (+8.5%), and jawline (+4.5%).* Participants also reported increased skin smoothness (+40%), radiance (+30%), and a reduction in wrinkles (-27%).**
Visible lifting appearance+
Innovative algorithm tracks changes in the skin structure. Arrows indicate the direction of the lift. Their length indicates the intensity of the lift.
Integrated skincare:
Incorporate this lightweight serum into your morning and evening routines. Apply after a Vitamin C serum and before moisturiser and sunscreen in the morning. In the evening, layer it after other serums. It’s Suitable for use in between ultrasound procedures.***
Expert opinion:
Dr Wassim Taktouk, aesthetic doctor, states: “The A.G.E. range is a breakthrough in anti-ageing skincare…I recommend this to my patients wanting an at-home treatment to improve signs of ageing caused by glycation…such as firmness, fine lines, wrinkles, and elasticity."
Join us on June 23 for a SkinCeuticals CPD-accredited medical learning live webinar. Learn from Dr Catherine Fairris, president of the British College of Aesthetic Medicine (BCAM), about glycation and advanced anti-ageing strategies. Sign up here.
