Effect analysis of intradermal hyaluronic acid injection to treat enlarged facial pores

A study published in the August issue of the Journal of Cosmetic Dermatology has investigated the clinical application and efficacy of intradermal injection of low molecular weight hyaluronic acid (LMW‐HA) for treating enlarged facial pores.

42 subjects who sought aesthetic treatment underwent intradermal injection of LMW‐HA to improve enlarged facial pores. For each treatment, 2.5 mL (25 mg) of LMW‐HA was injected into the skin of the full face. The treatment was repeated two to five times with an interval of one to one and a half months between consecutive treatments. The postoperative follow‐up period was one to six months. Statistical analysis was used to compare the degree of enlargement of facial pores before and after injection. The clinical efficacy and adverse effects were recorded.

The enlarged facial pores before and after treatment were categorised and subjected to the Wilcoxon matched‐pairs signed‐rank test. The difference was statistically significant (P<.01). The improvement rate was 40.03±18.41%. No infection, nodules, or pigmentation was reported at the injection sites in the subjects who sought aesthetic treatment. The overall satisfaction rate was 92.8%.

The authors concluded that intradermal injection of LMW‐HA can significantly improve skin texture, reduce pore size, and enhance skin radiance. The injection technique was simple, safe, and effective and could easily be extended to clinical practice.