As scientific understanding of the skin microbiome deepens, new therapeutic avenues are emerging - one of the most promising being the use of bacterial exosomes in clinical skin care.
Exosomes are nano-sized extracellular vesicles that act as cellular messengers, playing a vital role in skin homeostasis and regeneration. Derived from lactobacillus, a genus of bacteria naturally present in the skin’s microbiome, these exosomes are inherently recognisable to the skin.
This biological familiarity enhances their ability to penetrate effectively and integrate seamlessly into skin systems, making them uniquely suited for dermatological use.
Lactobacillus-derived exosomes exhibit superior bioavailability and structural stability compared to other exosome sources. They have been shown to support key skin functions by modulating inflammatory pathways, improving epidermal hydration, and reinforcing the skin barrier. Their antioxidant capacity helps neutralise oxidative stress and defend against environmental aggressors, making them a valuable asset in both age management and post-procedural care.
In clinical practice, this technology offers a biologically compatible adjunct to treatments such as microneedling, RF microneedling, and laser resurfacing. When paired with such procedures, lactobacillus-derived exosomes can hoenhance skin recovery, reduce downtime, and support visible improvements in texture, tone, and resilience.
As research continues to evolve, the potential for bacterial exosomes in dermatology is only beginning to be understood. With applications ranging from barrier repair to visible rejuvenation, their use represents a shift toward more biomimetic and regenerative approaches to skin care.
This is a sponsored story in association with Dermalogica for Professionals.