New study reveals polycaprolacton-based dermal filler induces neo-collagenesis

A study published in the Journal of Cosmetic and Laser Therapy has shown that the novel polycaprolactone (PCL) based dermal filler Ellanse is capable of inducing neo-collagenesis when injected intra-dermally in humant issue.

Patients were injected intra-dermally with the PCL-based dermal filler. Histological analysis of tissue obtained from the biopsies revealed that the filler showed collagen formation around the PCL particles which are maintained in their original sate 13 months post-injection.

Furthermore this indicates that tissue migration of the PCL particles did not occur.